The Guide is the first NPC you are supposed to meet. She is found at the first floor of the Shiguto apartments in right of the spawn.
Dialogue Transcript 
Edit
Welcome to neon district.
What is neon district? Edit
it is one of the largest unregulated Technology hubs in the world.
Anything I should look for? Edit
Neon district can be Dangerous, you need to be careful around The Watch and the Syndicates groups in this area
What is there to do here? Edit
There a plenty of business to do here you can shop, meet new people and explore the district.
I need more help (goes back to the beginning) Edit
What else can I help with?
Goodbye. Edit
to be added
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